Genetically engineered crops are safe for humans and animals to eat and have not caused increases in cancer, obesity, gastrointestinal illnesses, kidney disease, autism or allergies, an exhaustive report from the National Academies of Science released Tuesday found.

Work on the 388-page report began two years ago and was conducted by a committee of more than 50 scientists, researchers and agricultural and industry experts convened by the National Academies of Sciences, Engineering, and Medicine. It reviewed more than 900 studies and data covering the 20 years since genetically modified crops were first introduced.

Overall, genetically engineered (GE) crops saved farmers in the United States money but didn’t appear to increase crop yields. They have lowered pest populations in some areas, especially in the Midwest but increased the number of herbicide-resistant weeds in others. There’s also no evidence that GE crops have affected the population of monarch butterflies, the report said.

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