Starring Amy Poehler, Tina Fey, Ike Barinholtz, Dianne Wiest, James Brolin, Maya Rudolph, John Leguizamo; directed by Jason Moore; 118 minutes; R for crude sexual content and language throughout, and for drug use.

A lot of very talented and likable people came together to make “Sisters.” Stars Tina Fey and Amy Poehler are much beloved for their iconic TV characters, longtime “Saturday Night Live” writer Paula Pell contributes the screenplay, and “Pitch Perfect” director Jason Moore takes on helming duties.

It’s a shame then, that with all these fine creators, this scattershot comedy just doesn’t gel in the way that it should.

One of the main problems with “Sisters” is that stars Fey and Poehler, while clearly having fun together, are not on the same page in terms of their performance choices. Poehler is heartfelt and realistic as overly caring and concerned nurse Maura, while Fey performs a sloppily conceived caricature of trainwreck cougar party girl/single mom Kate.

The sisters are summoned back to their hometown of Orlando, Fla., because their parents have sold their cherished family home and need their adult children to pack up their high school bedrooms, filled with ’80s detritus. The sisters decide to throw one last rager for old time’s sake.

The party takes up much of the film’s duration, which at nearly two hours is far too long for a project this lightweight. “Sisters” just doesn’t cohere as a consistent piece. It doesn’t commit to one thing or another, so it’s an odd mash-up of middle-aged lady humor and “Neighbors” style raging.

Katie Walsh, Tribune News Service